Its likely your graphics card will be screwed in so take off the side of your case and get a screwdriver whilst your at it, there is also a switch just underneath the card you may have to use to lever the card out of its PCI port.

I would also suggest downloading the latest drivers once the card is in

Here is the nvidia site for graphics card drivers: http://www.nvidia.com/Download/index.aspx?lang=en-us

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